7UFH
Integrin alpha IIB beta3 complex with fradafiban (Mn/Ca)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Integrin alpha-IIb heavy chain | polymer | 457 | 49516.0 | 2 | UniProt (P08514) Pfam (PF01839) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Isoform Beta-3C of Integrin beta-3 | polymer | 472 | 52087.9 | 2 | UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa,GPIIIa |
| 3 | E, G (E, H) | 10E5 Fab heavy chain | polymer | 221 | 23766.5 | 2 | Mus musculus (mouse) | ||
| 4 | F, H (F, L) | 10E5 Fab light chain | polymer | 214 | 23332.7 | 2 | Mus musculus (mouse) | ||
| 5 | I (G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | J, L (I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 7 | K (J) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | BA, CA, IA, M, N... (C, A, L) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 9 | P (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 10 | EA, FA, GA, HA, Q... (C, A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 11 | KA, LA, MA, V, W... (D, B) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 12 | NA, Y (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 13 | OA, Z (D, B) | Fradafiban | non-polymer | 367.4 | 2 | Chemie (MWX) | |||
| 14 | AA, DA, JA, PA (B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 15 | RA, SA, TA, UA, VA... (A, B, C, D, E...) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 297406.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2508.3 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 2829.9 | |
| All* | Total formula weight | 302744.2 |
