7UDB
Cryo-EM structure of a synaptobrevin-Munc18-1-syntaxin-1 complex class 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Syntaxin-binding protein 1 | polymer | 607 | 68714.9 | 1 | UniProt (P61765) Pfam (PF00995) In PDB | Rattus norvegicus (Norway rat) | N-Sec1,Protein unc-18 homolog 1,Unc18-1,Protein unc-18 homolog A,Unc-18A,p67,rbSec1 |
2 | B | Syntaxin-1A | polymer | 254 | 29221.5 | 1 | UniProt (P32851) Pfam (PF00804) Pfam (PF05739) In PDB | Rattus norvegicus (Norway rat) | Neuron-specific antigen HPC-1,Synaptotagmin-associated 35 kDa protein,P35A |
3 | C | Synaptobrevin-2 | polymer | 59 | 6645.4 | 1 | UniProt (P63045) Pfam (PF00957) In PDB | Rattus norvegicus (Norway rat) | VAMP-2,Vesicle-associated membrane protein 2 |
Sequence modifications
A: 1 - 594 (UniProt: P61765)
B: 2 - 253 (UniProt: P32851)
C: 29 - 83 (UniProt: P63045)
PDB | External Database | Details |
---|---|---|
Gly -12 | - | expression tag |
Ser -11 | - | expression tag |
Pro -10 | - | expression tag |
Gly -9 | - | expression tag |
Ile -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Gly -5 | - | expression tag |
Gly -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Ile -1 | - | expression tag |
His 0 | - | expression tag |
Lys 326 | Asp 326 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Ala 145 | Cys 145 | engineered mutation |
Ala 165 | Leu 165 | engineered mutation |
Ala 166 | Glu 166 | engineered mutation |
Cys 205 | Leu 205 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 25 | - | expression tag |
Ser 26 | - | expression tag |
Met 27 | - | expression tag |
Trp 28 | - | expression tag |
Cys 36 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 104581.8 | |
All* | Total formula weight | 104581.8 |