7U9F

Integrin alaphIIBbeta3 complex with BMS compound 4 in Mn2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Integrin alpha-IIb	polymer	454	49228.6	2	UniProt (P08514) Pfam (PF01839) In PDB	Homo sapiens (human)	GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb
2	B, D	Integrin beta-3	polymer	471	51958.8	2	UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIIa,GPIIIa
3	E, H	Fab heavy chain	polymer	216	23339.1	2		Mus musculus (mouse)
4	F, L	Fab light chain	polymer	214	23332.7	2		Mus musculus (mouse)
5	G	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
6	I, K	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
7	J	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
8	C, A, L	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
9	C, A	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
10	D, B	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
11	D, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
12	D, B	(4-{[(5S)-3-{4-[(E)-imino(4-methylpiperazin-1-yl)methyl]phenyl}-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid	non-polymer		428.5	2	Chemie (I7R)
13	C, D	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
14		water	water		18.0	1104	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	295718.3
Branched	Number of molecules	4
	Total formula weight	2508.3
Non-Polymers*	Number of molecules	29
	Total formula weight	2885.2
All*	Total formula weight	301111.8

*Water molecules are not included.