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7U7E

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 60s

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41synthetic construct
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3')polymer82426.61synthetic construct
4D, E, G
(A, P)
MANGANESE (II) IONnon-polymer54.93Chemie (MN)
5F
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
6H, I, J
(A, T, P)
waterwater18.0450Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54681.7
Non-Polymers*Number of molecules4
Total formula weight672.0
All*Total formula weight55353.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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