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7U36

Crystal structure of human GSK3B in complex with ARN1484

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glycogen synthase kinase-3 betapolymer35139930.92UniProt (P49841)
Pfam (PF00069)
Homo sapiens (human)GSK-3 beta,Serine/threonine-protein kinase GSK3B
2C, E
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3D, F
(A, B)
(3S)-1-[(2-fluorophenoxy)acetyl]-N-(pyridin-2-yl)pyrrolidine-3-carboxamidenon-polymer343.42Chemie (L7W)
4G, H
(A, B)
waterwater18.025Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79861.8
Non-Polymers*Number of molecules4
Total formula weight757.6
All*Total formula weight80619.5
*Water molecules are not included.

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PDB entries from 2024-12-18

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