7U2P
Structure of TcdA GTD in complex with RhoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucosyltransferase TcdA | polymer | 543 | 62919.0 | 1 | UniProt (P16154) Pfam (PF12918) Pfam (PF12919) | Clostridioides difficile | |
| 2 | B (B) | Transforming protein RhoA | polymer | 186 | 20891.9 | 1 | UniProt (Q9QUI0) Pfam (PF00071) UniProt (by SIFTS) (P61586) | Homo sapiens (human) | |
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 1 | Chemie (UPG) | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 7 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | H, I (A, B) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A: 1 - 542 (UniProt: P16154)
B: 1 - 181 (UniProt: Q9QUI0)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 190 | Lys 190 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 37 | Thr 37 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83810.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1184.8 | |
| All* | Total formula weight | 84995.7 |
