7U22
Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-directed RNA polymerase subunit alpha | polymer | 347 | 37745.3 | 2 | UniProt (A5U8D3) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) UniProt (by SIFTS) (P9WGZ1) In PDB | Mycobacterium tuberculosis | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C | DNA-directed RNA polymerase subunit beta | polymer | 1178 | 130018.8 | 1 | UniProt (P9WGY8) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P9WGY9) In PDB | Mycobacterium tuberculosis | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D | DNA-directed RNA polymerase subunit beta' | polymer | 1316 | 146969.0 | 1 | UniProt (A0A045J9E2) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) UniProt (by SIFTS) (P9WGY7) In PDB | Mycobacterium tuberculosis | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E | DNA-directed RNA polymerase subunit omega | polymer | 110 | 11851.1 | 1 | UniProt (A0A045H2R3) Pfam (PF01192) UniProt (by SIFTS) (P9WGY5) In PDB | Mycobacterium tuberculosis | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F | RNA polymerase sigma factor SigA | polymer | 528 | 57877.2 | 1 | UniProt (A0A045HD00) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) UniProt (by SIFTS) (P9WGI1) In PDB | Mycobacterium tuberculosis | |
| 6 | G | T DNA | polymer | 16 | 4939.2 | 1 | Mycobacterium tuberculosis | ||
| 7 | H | NT DNA | polymer | 23 | 7160.6 | 1 | Mycobacterium tuberculosis | ||
| 8 | C | (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate | non-polymer | 917.1 | 1 | Chemie (KYO) | |||
| 9 | D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 10 | D | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 434306.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1072.3 | |
| All* | Total formula weight | 435378.9 |
