7U17
TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Transmembrane protein 106B | polymer | 135 | 15488.7 | 3 | UniProt (Q9NUM4) Pfam (PF07092) | Homo sapiens (human) | |
| 2 | D, E, F, G, H... (B, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
B, A, C: 120 - 254 (UniProt: Q9NUM4)
| PDB | External Database | Details |
|---|---|---|
| Ser 185 | Thr 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46466.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 49120.5 |
