7U0G
structure of LIN28b nucleosome bound 3 OCT4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
2 | B, F | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (human) | |
3 | C, G | Histone H2A type 2-C | polymer | 129 | 14017.4 | 2 | UniProt (Q16777) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | H2A-clustered histone 20,Histone H2A-GL101,Histone H2A/q |
4 | D, H | Histone H2B type 2-E | polymer | 126 | 13951.2 | 2 | UniProt (Q16778) Pfam (PF00125) In PDB | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
5 | I | DNA (162-MER) | polymer | 162 | 50398.3 | 1 | GenBank (2225930) | Homo sapiens | |
6 | J | DNA (162-MER) | polymer | 162 | 49595.7 | 1 | GenBank (2225930) | Homo sapiens | |
7 | K, L, M | Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 | polymer | 550 | 61269.7 | 3 | UniProt (A0A376KDN7) UniProt (Q01860) Pfam (PF01547) Pfam (PF00157) Pfam (PF00046) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli K-12 | Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3 |
8 | N, O | Single-chain variable fragment | polymer | 265 | 29030.1 | 2 | Mus musculus |
Sequence modifications
K, L, M: -248 - 118 (UniProt: A0A376KDN7)
K, L, M: 138 - 290 (UniProt: Q01860)
PDB | External Database | Details |
---|---|---|
Met -251 | - | initiating methionine |
Lys -250 | - | expression tag |
Glu -249 | - | expression tag |
Unk 1 | Thr 275 | conflict |
Ala 114 | Lys 388 | conflict |
Ala 115 | Asp 389 | conflict |
Asn 119 | - | linker |
Ala 120 | - | linker |
Gly 121 | - | linker |
Ser 122 | - | linker |
Glu 123 | - | linker |
Asn 124 | - | linker |
Leu 125 | - | linker |
Tyr 126 | - | linker |
Phe 127 | - | linker |
Gln 128 | - | linker |
Gly 129 | - | linker |
Ser 130 | - | linker |
Val 131 | - | linker |
Asp 132 | - | linker |
Ser 133 | - | linker |
Ala 134 | - | linker |
Ala 135 | - | linker |
Ala 136 | - | linker |
Ser 137 | - | linker |
PDB | External Database | Details |
---|---|---|
Glu 291 | - | expression tag |
Phe 292 | - | expression tag |
His 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 451463.9 | |
All* | Total formula weight | 451463.9 |