7U0G
structure of LIN28b nucleosome bound 3 OCT4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 2-C | polymer | 129 | 14017.4 | 2 | UniProt (Q16777) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A-clustered histone 20,Histone H2A-GL101,Histone H2A/q |
| 4 | D, H (D, H) | Histone H2B type 2-E | polymer | 126 | 13951.2 | 2 | UniProt (Q16778) Pfam (PF00125) | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
| 5 | I (I) | DNA (162-MER) | polymer | 162 | 50398.3 | 1 | GenBank (2225930) | Homo sapiens | |
| 6 | J (J) | DNA (162-MER) | polymer | 162 | 49595.7 | 1 | GenBank (2225930) | Homo sapiens | |
| 7 | K, L, M (K, L, M) | Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 | polymer | 550 | 61269.7 | 3 | UniProt (A0A376KDN7) UniProt (Q01860) Pfam (PF01547) Pfam (PF00157) Pfam (PF00046) UniProt (by SIFTS) (P0AEX9) | Escherichia coli K-12 | Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3 |
| 8 | N, O (N, O) | Single-chain variable fragment | polymer | 265 | 29030.1 | 2 | Mus musculus |
Sequence modifications
K, L, M: -248 - 118 (UniProt: A0A376KDN7)
K, L, M: 138 - 290 (UniProt: Q01860)
| PDB | External Database | Details |
|---|---|---|
| Met -251 | - | initiating methionine |
| Lys -250 | - | expression tag |
| Glu -249 | - | expression tag |
| Unk 1 | Thr 275 | conflict |
| Ala 114 | Lys 388 | conflict |
| Ala 115 | Asp 389 | conflict |
| Asn 119 | - | linker |
| Ala 120 | - | linker |
| Gly 121 | - | linker |
| Ser 122 | - | linker |
| Glu 123 | - | linker |
| Asn 124 | - | linker |
| Leu 125 | - | linker |
| Tyr 126 | - | linker |
| Phe 127 | - | linker |
| Gln 128 | - | linker |
| Gly 129 | - | linker |
| Ser 130 | - | linker |
| Val 131 | - | linker |
| Asp 132 | - | linker |
| Ser 133 | - | linker |
| Ala 134 | - | linker |
| Ala 135 | - | linker |
| Ala 136 | - | linker |
| Ser 137 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 291 | - | expression tag |
| Phe 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 451463.9 | |
| All* | Total formula weight | 451463.9 |
