7U0D

Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Surface glycoprotein	polymer	196	22297.2	1	UniProt (A0A7U3CI26) Pfam (PF09408) UniProt (by SIFTS) (P0DTC2) In PDB	Severe acute respiratory syndrome coronavirus 2
2	M	Heavy chain of SARS-CoV-2 antibody A19-46.1	polymer	231	24869.9	1		Homo sapiens
3	N	Light chain of SARS-CoV-2 antibody A19-46.1	polymer	216	22760.3	1		Homo sapiens
4	O	Heavy chain of SARS-CoV-2 antibody B1-182.1	polymer	228	24285.3	1		Homo sapiens
5	P	Light chain of SARS-CoV-2 antibody B1-182.1	polymer	215	23536.0	1		Homo sapiens
6	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

B: 331 - 526 (UniProt: A0A7U3CI26)

PDB	External Database	Details
Asp 339	Gly 16	variant
Leu 371	Ser 48	variant
Pro 373	Ser 50	variant
Phe 375	Ser 52	variant
Lys 440	Asn 117	variant
Ser 446	Gly 123	variant
Asn 477	Ser 154	variant
Lys 478	Thr 155	variant
Ala 484	Lys 161	variant
Arg 493	Gln 170	variant
Ser 496	Gly 173	variant
Arg 498	Gln 175	variant
His 505	Tyr 182	variant

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	117748.7
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	117969.9

*Water molecules are not included.