7U0D
Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Surface glycoprotein | polymer | 196 | 22297.2 | 1 | UniProt (A0A7U3CI26) Pfam (PF09408) UniProt (by SIFTS) (P0DTC2) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (M) | Heavy chain of SARS-CoV-2 antibody A19-46.1 | polymer | 231 | 24869.9 | 1 | Homo sapiens | ||
| 3 | C (N) | Light chain of SARS-CoV-2 antibody A19-46.1 | polymer | 216 | 22760.3 | 1 | Homo sapiens | ||
| 4 | D (O) | Heavy chain of SARS-CoV-2 antibody B1-182.1 | polymer | 228 | 24285.3 | 1 | Homo sapiens | ||
| 5 | E (P) | Light chain of SARS-CoV-2 antibody B1-182.1 | polymer | 215 | 23536.0 | 1 | Homo sapiens | ||
| 6 | F (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
B: 331 - 526 (UniProt: A0A7U3CI26)
| PDB | External Database | Details |
|---|---|---|
| Asp 339 | Gly 16 | variant |
| Leu 371 | Ser 48 | variant |
| Pro 373 | Ser 50 | variant |
| Phe 375 | Ser 52 | variant |
| Lys 440 | Asn 117 | variant |
| Ser 446 | Gly 123 | variant |
| Asn 477 | Ser 154 | variant |
| Lys 478 | Thr 155 | variant |
| Ala 484 | Lys 161 | variant |
| Arg 493 | Gln 170 | variant |
| Ser 496 | Gly 173 | variant |
| Arg 498 | Gln 175 | variant |
| His 505 | Tyr 182 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 117748.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 117969.9 |
