7TZJ
SARS CoV-2 PLpro in complex with inhibitor 3k
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Papain-like protease | polymer | 318 | 35927.7 | 2 | UniProt (P0DTC1) Pfam (PF08715) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3, nsp3, PL2-PRO, Papain-like proteinase, PL-PRO |
| 2 | C, I (A, B) | N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide | non-polymer | 390.5 | 2 | Chemie (S88) | |||
| 3 | D, E, F, G, J... (A, B) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
| 4 | H, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | P, Q (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 315 (UniProt: P0DTC1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 111 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71855.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1525.9 | |
| All* | Total formula weight | 73381.3 |
