7TYR

Cryo-EM structure of the basal state of the Artemis:DNA-PKcs complex (see COMPND 13/14)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA-dependent protein kinase catalytic subunit	polymer	4128	469673.2	1	UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260)	Homo sapiens (human)	DNA-PKcs,DNPK1,p460
2	B (C)	Protein artemis	polymer	707	80493.4	1	UniProt (Q96SD1) Pfam (PF07522)	Homo sapiens (human)	DNA cross-link repair 1C protein,Protein A-SCID,SNM1 homolog C,hSNM1C,SNM1-like protein

Sequence modifications

C: 1 - 692 (UniProt: Q96SD1)

PDB	External Database	Details
Glu 693	-	expression tag
Asn 694	-	expression tag
Leu 695	-	expression tag
Tyr 696	-	expression tag
Phe 697	-	expression tag
Gln 698	-	expression tag
Gly 699	-	expression tag
His 700	-	expression tag
His 701	-	expression tag
His 702	-	expression tag
His 703	-	expression tag
His 704	-	expression tag
His 705	-	expression tag
His 706	-	expression tag
His 707	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	550166.6
All*	Total formula weight	550166.6

*Water molecules are not included.