7TWV
Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at pH 5 (P43 crystal form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Non-structural protein 3 | polymer | 169 | 18178.8 | 2 | UniProt (P0DTD1) Pfam (PF01661) | Severe acute respiratory syndrome coronavirus 2 | nsp3, PL2-PRO, Papain-like protease, Papain-like proteinase, PL-PRO |
| 2 | C (A) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 1 | Chemie (AR6) PubChem (192) PubChem (445794) PubChem (447048) PubChem (10437766) PubChem (25113622) PubChem (25113623) PubChem (44415180) PubChem (44144391) PubChem (51051599) PubChem (33576) PubChem (447165) PubChem (448826) PubChem (9548001) PubChem (9547960) PubChem (174159053) PubChem (89379870) PubChem (91746164) PubChem (122606931) PubChem (122609061) PubChem (140853820) PubChem (146879505) PubChem (162774256) PubChem (162782217) PubChem (163972867) PubChem (173750345) PubChem (173750346) PubChem (175675949) | |||
| 3 | D, E (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) PubChem (311) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 698 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 169 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36357.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 943.6 | |
| All* | Total formula weight | 37301.1 |
