7TVJ
Crystal Structure of Monobody Mb(SHP2PTP_13)/SHP2 PTP Domain Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 304 | 35293.0 | 2 | UniProt (Q06124) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3 |
| 2 | B, D (B, E) | Mb(SHP2PTP_13) | polymer | 94 | 10098.1 | 2 | synthetic construct | ||
| 3 | E, F (A, D) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 4 | G, H, I, J (A, B, D, E) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A, D: 224 - 525 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Gly 222 | - | expression tag |
| Ser 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90782.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 378.2 | |
| All* | Total formula weight | 91160.3 |
