7TU9
Alpha1/BetaB Heteromeric Glycine Receptor in Strychnine-Bound State
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, C, B) | Glycine receptor subunit alphaZ1 | polymer | 458 | 52537.6 | 4 | UniProt (O93430) Pfam (PF02931) Pfam (PF02932) | Danio rerio (zebrafish) | |
| 2 | E (E) | Glycine receptor beta subunit 2 | polymer | 591 | 65820.3 | 1 | UniProt (Q6DC22) Pfam (PF02931) Pfam (PF02932) | Danio rerio (zebrafish) | Glycine receptor,beta b |
| 3 | F, FA, GA, K, S... (A, E, D, C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | AA, G, HA, IA, J... (B, A, E, D, C) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 10 | Chemie (PIO) PubChem (16219852) PubChem (52946598) PubChem (49867504) PubChem (53394310) PubChem (73441659) PubChem (124587602) PubChem (131850384) PubChem (132274717) PubChem (99649229) PubChem (9543520) PubChem (136212530) PubChem (136212534) | |||
| 5 | BA, CA, DA, EA, H... (B, E, A, D, C) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 10 | Chemie (PX4) PubChem (26198) PubChem (87505) PubChem (5313082) | |||
| 6 | I, L, T, W, X (A, D, C, B) | STRYCHNINE | non-polymer | 334.4 | 5 | Chemie (SY9) PubChem (16757746) PubChem (16759292) PubChem (16760012) PubChem (5304) PubChem (23423987) PubChem (23636622) PubChem (24011700) PubChem (25022186) PubChem (44135720) PubChem (121457) PubChem (54235484) PubChem (3035321) PubChem (441071) PubChem (51035301) PubChem (71057032) PubChem (71073285) PubChem (74892805) PubChem (75539564) PubChem (3037422) PubChem (3083694) PubChem (68315627) PubChem (5979) PubChem (3246505) PubChem (5321532) PubChem (98049551) PubChem (5702135) PubChem (5705187) PubChem (9840646) PubChem (9997016) PubChem (6604670) PubChem (98049553) PubChem (133611800) PubChem (100078880) PubChem (124352578) PubChem (124389223) PubChem (11336581) PubChem (12359078) PubChem (124803013) PubChem (134814445) PubChem (134944247) PubChem (142877741) PubChem (149063339) PubChem (155935641) PubChem (162987392) PubChem (162987393) PubChem (162987394) PubChem (162987395) PubChem (162987396) PubChem (173470783) |
Sequence modifications
A, D, C, B: 1 - 444 (UniProt: O93430)
E: -80 - 494 (UniProt: Q6DC22)
| PDB | External Database | Details |
|---|---|---|
| Leu 445 | - | expression tag |
| Val 446 | - | expression tag |
| Pro 447 | - | expression tag |
| Arg 448 | - | expression tag |
| Gly 449 | - | expression tag |
| Ser 450 | - | expression tag |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Trp -51 | - | insertion |
| Ser -50 | - | insertion |
| His -49 | - | insertion |
| Pro -48 | - | insertion |
| Gln -47 | - | insertion |
| Phe -46 | - | insertion |
| Glu -45 | - | insertion |
| Lys -44 | - | insertion |
| Gly -43 | - | insertion |
| Gly -42 | - | insertion |
| Gly -41 | - | insertion |
| Ser -40 | - | insertion |
| Gly -39 | - | insertion |
| Gly -38 | - | insertion |
| Gly -37 | - | insertion |
| Ser -36 | - | insertion |
| Gly -35 | - | insertion |
| Gly -34 | - | insertion |
| Gly -33 | - | insertion |
| Ser -32 | - | insertion |
| Trp -31 | - | insertion |
| Ser -30 | - | insertion |
| His -29 | - | insertion |
| Pro -28 | - | insertion |
| Gln -27 | - | insertion |
| Phe -26 | - | insertion |
| Glu -25 | - | insertion |
| Lys -24 | - | insertion |
| Gly -23 | - | insertion |
| Gly -22 | - | insertion |
| Gly -21 | - | insertion |
| Ser -20 | - | insertion |
| Gly -19 | - | insertion |
| Gly -18 | - | insertion |
| Gly -17 | - | insertion |
| Ser -16 | - | insertion |
| Gly -15 | - | insertion |
| Gly -14 | - | insertion |
| Gly -13 | - | insertion |
| Ser -12 | - | insertion |
| Trp -11 | - | insertion |
| Ser -10 | - | insertion |
| His -9 | - | insertion |
| Pro -8 | - | insertion |
| Gln -7 | - | insertion |
| Phe -6 | - | insertion |
| Glu -5 | - | insertion |
| Lys -4 | - | insertion |
| Gly -3 | - | insertion |
| Gly -2 | - | insertion |
| Gly -1 | - | insertion |
| Ser 0 | - | insertion |
| Gly 1 | - | insertion |
| Gly 2 | - | insertion |
| Gly 3 | - | insertion |
| Ser 4 | - | insertion |
| Gly 5 | - | insertion |
| Gly 6 | - | insertion |
| Gly 7 | - | insertion |
| Ser 8 | - | insertion |
| Trp 9 | - | insertion |
| Ser 10 | - | insertion |
| His 11 | - | insertion |
| Pro 12 | - | insertion |
| Gln 13 | - | insertion |
| Phe 14 | - | insertion |
| Glu 15 | - | insertion |
| Lys 16 | - | insertion |
| Glu 17 | - | insertion |
| Asn 18 | - | insertion |
| Leu 19 | - | insertion |
| Tyr 20 | - | insertion |
| Phe 21 | - | insertion |
| Gln 22 | - | insertion |
| Gly 23 | - | insertion |
| Glu 24 | - | insertion |
| Lys 25 | - | insertion |
| Ser 26 | - | insertion |
| Ala 27 | - | insertion |
| Lys 28 | - | insertion |
| Lys 29 | - | insertion |
| Glu 495 | - | expression tag |
| Asn 496 | - | expression tag |
| Leu 497 | - | expression tag |
| Tyr 498 | - | expression tag |
| Phe 499 | - | expression tag |
| Gln 500 | - | expression tag |
| Gly 501 | - | expression tag |
| Thr 502 | - | expression tag |
| Glu 503 | - | expression tag |
| Thr 504 | - | expression tag |
| Ser 505 | - | expression tag |
| Gln 506 | - | expression tag |
| Val 507 | - | expression tag |
| Ala 508 | - | expression tag |
| Pro 509 | - | expression tag |
| Ala 510 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 275970.7 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 17254.4 | |
| All* | Total formula weight | 293225.0 |
