7TT8
Human LRH-1 LBD bound to agonist 6N-10CA and fragment of Tif2 coactivator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor subfamily 5 group A member 2 | polymer | 246 | 28401.8 | 1 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (human) | Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1 |
| 2 | B (C) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C (A) | 10-[(3aR,6S,6aR)-3-phenyl-3a-(1-phenylethenyl)-6-(sulfamoylamino)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid (non-preferred name) | non-polymer | 550.8 | 1 | Chemie (IUW) | |||
| 4 | D (A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 299 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ser 296 | - | expression tag |
| Asn 297 | - | expression tag |
| Ala 298 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30110.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 550.8 | |
| All* | Total formula weight | 30661.5 |
