7TRO
Crystal structure of R14A-R20A human Galectin-7 mutant in presence of lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-7 | polymer | 135 | 14793.6 | 2 | UniProt (P47929) Pfam (PF00337) | Homo sapiens (human) | Gal-7,HKL-14,PI7,p53-induced gene 1 protein |
| 2 | C (C) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | |||
| 3 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 135 (UniProt: P47929)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Arg 15 | engineered mutation |
| Ala 20 | Arg 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29587.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 30113.7 |
