7TRG
The beta-tubulin folding intermediate I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin beta chain | polymer | 444 | 49717.6 | 1 | UniProt (P07437) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (human) | Tubulin beta-5 chain |
| 2 | B (B) | T-complex protein 1 subunit theta | polymer | 547 | 59576.3 | 1 | UniProt (P50990) Pfam (PF00118) | Homo sapiens (human) | TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15 |
| 3 | C (C) | T-complex protein 1 subunit eta | polymer | 553 | 60579.7 | 1 | UniProt (Q99832) Pfam (PF00118) | Homo sapiens (human) | TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein |
| 4 | D (D) | T-complex protein 1 subunit epsilon | polymer | 541 | 59750.0 | 1 | UniProt (P48643) Pfam (PF00118) | Homo sapiens (human) | TCP-1-epsilon,CCT-epsilon |
| 5 | E (E) | T-complex protein 1 subunit beta | polymer | 535 | 57567.1 | 1 | UniProt (P78371) Pfam (PF00118) | Homo sapiens (human) | TCP-1-beta,CCT-beta |
| 6 | F (F) | T-complex protein 1 subunit delta | polymer | 539 | 57996.1 | 1 | UniProt (P50991) Pfam (PF00118) | Homo sapiens (human) | TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding |
| 7 | G (G) | T-complex protein 1 subunit alpha | polymer | 556 | 60418.5 | 1 | UniProt (P17987) Pfam (PF00118) | Homo sapiens (human) | TCP-1-alpha,CCT-alpha |
| 8 | H (H) | T-complex protein 1 subunit gamma | polymer | 545 | 60613.9 | 1 | UniProt (P49368) Pfam (PF00118) | Homo sapiens (human) | TCP-1-gamma,CCT-gamma,hTRiC5 |
| 9 | I (I) | T-complex protein 1 subunit zeta | polymer | 531 | 58166.2 | 1 | UniProt (P40227) Pfam (PF00118) | Homo sapiens (human) | TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20 |
| 10 | BA, EA, J, M, P... (H, I, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 11 | CA, FA, K, N, Q... (H, I, B, C, D...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) | |||
| 12 | AA, DA, GA, L, O... (G, H, I, B, C...) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 8 | Chemie (AF3) | |||
| 13 | HA, IA, JA, KA, LA... (B, C, D, E, F...) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
C: 1 - 554 (UniProt: Q99832)
I: 1 - 531 (UniProt: P40227)
| PDB | External Database | Details |
|---|---|---|
| Gly 473 | - | insertion |
| Ser 474 | - | insertion |
| His 475 | - | insertion |
| His 476 | - | insertion |
| His 477 | - | insertion |
| His 478 | - | insertion |
| His 479 | - | insertion |
| His 480 | - | insertion |
| Gly 481 | - | insertion |
| Ser 482 | - | insertion |
| Arg 535 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Phe 528 | Ser 528 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 524385.4 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 4283.9 | |
| All* | Total formula weight | 528669.3 |
