7TRF
Human telomerase catalytic core RNP with H2A/H2B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Histone H2B type 1-C/E/F/G/I | polymer | 126 | 13937.2 | 1 | UniProt (P62807) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
| 2 | B (E) | Histone H2A | polymer | 129 | 14047.5 | 1 | UniProt (A0A024RAS2) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (Q9BTM1) | Homo sapiens (human) | |
| 3 | C (B) | Telomerase RNA, partial sequence | polymer | 451 | 145477.8 | 1 | GenBank (1932797) | Homo sapiens (human) | |
| 4 | D (A) | Telomerase reverse transcriptase | polymer | 1167 | 130711.5 | 1 | UniProt (O14746) Pfam (PF12009) Pfam (PF00078) Pfam (PF21399) | Homo sapiens (human) | HEST2,Telomerase catalytic subunit,Telomerase-associated protein 2,TP2 |
| 5 | E (D) | Telomeric repeat substrate | polymer | 18 | 5514.6 | 1 | Homo sapiens |
Sequence modifications
A: 1 - 1132 (UniProt: O14746)
| PDB | External Database | Details |
|---|---|---|
| Gly -34 | - | expression tag |
| His -33 | - | expression tag |
| Met -32 | - | expression tag |
| Ser -31 | - | expression tag |
| Ala -30 | - | expression tag |
| Trp -29 | - | expression tag |
| Ser -28 | - | expression tag |
| His -27 | - | expression tag |
| Pro -26 | - | expression tag |
| Gln -25 | - | expression tag |
| Phe -24 | - | expression tag |
| Glu -23 | - | expression tag |
| Lys -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Ala -10 | - | expression tag |
| Trp -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 309688.5 | |
| All* | Total formula weight | 309688.5 |
