7TR7
APE1 product complex with abasic ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-(apurinic or apyrimidinic site) lyase | polymer | 276 | 31156.5 | 2 | UniProt (P27695) Pfam (PF03372) In PDB | Homo sapiens (human) | APEX1, APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1, APE-1, REF-1, Redox factor-1 |
| 2 | D, C | DNA (5'-D(P*(3DR)P*CP*GP*AP*TP*GP*C)-3') | polymer | 7 | 1989.3 | 2 | synthetic construct | ||
| 3 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Ala 138 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66291.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 66340.2 |
