7TP4

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	Z	Spike protein S1	polymer	205	23104.9	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	K398.22 heavy chain	polymer	227	24160.1	1		Macaca mulatta (Rhesus monkey)
3	L	K398.22 light chain	polymer	214	22520.8	1		Macaca mulatta (Rhesus monkey)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	L	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6		water	water		18.0	305	Chemie (HOH)

Sequence modifications

Z: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69785.8
Branched	Number of molecules	1
	Total formula weight	570.5
Non-Polymers*	Number of molecules	1
	Total formula weight	62.1
All*	Total formula weight	70418.4

*Water molecules are not included.