7TOP
Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A25S) | 25S rRNA | polymer | 3396 | 1097493.9 | 1 | GenBank (834774822) | Saccharomyces cerevisiae (baker's yeast) | |
| 2 | B (A58S) | 5.8S rRNA | polymer | 158 | 50682.9 | 1 | GenBank (1267176496) | Saccharomyces cerevisiae (baker's yeast) | |
| 3 | C (A5S) | 5S rRNA | polymer | 121 | 38951.1 | 1 | GenBank (1039024045) | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | D (AL02) | 60S ribosomal protein L2-A | polymer | 254 | 27463.6 | 1 | UniProt (P0CX45) Pfam (PF00181) Pfam (PF03947) | Saccharomyces cerevisiae (baker's yeast) | L5,Large ribosomal subunit protein uL2-A,RP8,YL6 |
| 5 | E (AL03) | RPL3 isoform 1 | polymer | 387 | 43850.8 | 1 | UniProt (A0A6A5Q627) | Saccharomyces cerevisiae (baker's yeast) | |
| 6 | F (AL04) | RPL4A isoform 1 | polymer | 362 | 39159.1 | 1 | UniProt (A0A6A5Q3W0) | Saccharomyces cerevisiae (baker's yeast) | |
| 7 | G (AL05) | RPL5 isoform 1 | polymer | 297 | 33764.8 | 1 | UniProt (A0A6A5Q0W8) | Saccharomyces cerevisiae (baker's yeast) | |
| 8 | H (AL06) | 60S ribosomal protein L6-A | polymer | 176 | 20000.6 | 1 | UniProt (Q02326) Pfam (PF01159) | Saccharomyces cerevisiae (baker's yeast) | L17,Large ribosomal subunit protein eL6-A,RP18,YL16 |
| 9 | I (AL07) | 60S ribosomal protein L7-A | polymer | 244 | 27686.3 | 1 | UniProt (P05737) Pfam (PF08079) Pfam (PF00327) | Saccharomyces cerevisiae (baker's yeast) | L6,Large ribosomal subunit protein uL30-A,RP11,YL8 |
| 10 | J (AL08) | 60S ribosomal protein L8-A | polymer | 256 | 28175.8 | 1 | UniProt (P17076) Pfam (PF01248) | Saccharomyces cerevisiae (baker's yeast) | L4,L4-2,L7a-1,Large ribosomal subunit protein eL8-A,Maintenance of killer protein 7,RP6,YL5 |
| 11 | K (AL09) | 60S ribosomal protein L9-A | polymer | 191 | 21605.1 | 1 | UniProt (P05738) Pfam (PF00347) | Saccharomyces cerevisiae (baker's yeast) | L8,Large ribosomal subunit protein uL6-A,RP24,YL11 |
| 12 | L (AL10) | RPL10 isoform 1 | polymer | 221 | 25410.5 | 1 | UniProt (A0A6A5PUZ5) | Saccharomyces cerevisiae (baker's yeast) | |
| 13 | M (AL11) | RPL11A isoform 1 | polymer | 174 | 19755.7 | 1 | UniProt (A0A6A5Q7I9) | Saccharomyces cerevisiae (baker's yeast) | |
| 14 | N (AL12) | Ribosomal protein L12 | polymer | 155 | 13209.3 | 1 | Saccharomyces cerevisiae (baker's yeast) | ||
| 15 | O (AL13) | 60S ribosomal protein L13-A | polymer | 199 | 22604.2 | 1 | UniProt (Q12690) Pfam (PF01294) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL13-A |
| 16 | P (AL14) | 60S ribosomal protein L14-A | polymer | 138 | 15195.1 | 1 | UniProt (P36105) Pfam (PF00467) Pfam (PF01929) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL14-A |
| 17 | Q (AL15) | 60S ribosomal protein L15-A | polymer | 204 | 24482.4 | 1 | UniProt (P05748) Pfam (PF00827) | Saccharomyces cerevisiae (baker's yeast) | L13,Large ribosomal subunit protein eL15-A,RP15R,YL10,YP18 |
| 18 | R (AL16) | 60S ribosomal protein L16-A | polymer | 199 | 22247.2 | 1 | UniProt (P26784) Pfam (PF00572) | Saccharomyces cerevisiae (baker's yeast) | L13a,L21,Large ribosomal subunit protein uL13-A,RP22,YL15 |
| 19 | S (AL17) | 60S ribosomal protein L17-A | polymer | 184 | 20589.5 | 1 | UniProt (P05740) Pfam (PF00237) | Saccharomyces cerevisiae (baker's yeast) | L20A,Large ribosomal subunit protein uL22-A,YL17 |
| 20 | T (AL18) | 60S ribosomal protein L18-A | polymer | 186 | 20609.3 | 1 | UniProt (P0CX49) Pfam (PF17135) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL18-A,RP28 |
| 21 | U (AL19) | 60S ribosomal protein L19-A | polymer | 189 | 21762.3 | 1 | UniProt (P0CX82) Pfam (PF01280) | Saccharomyces cerevisiae (baker's yeast) | L23,Large ribosomal subunit protein eL19-A,RP15L,RP33,YL14 |
| 22 | V (AL20) | 60S ribosomal protein L20-A | polymer | 172 | 20478.9 | 1 | UniProt (P0CX23) Pfam (PF01775) | Saccharomyces cerevisiae (baker's yeast) | L18a,Large ribosomal subunit protein eL20-A |
| 23 | W (AL21) | 60S ribosomal protein L21-A | polymer | 160 | 18279.3 | 1 | UniProt (Q02753) Pfam (PF01157) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL21-A |
| 24 | X (AL22) | 60S ribosomal protein L22-A | polymer | 121 | 13711.4 | 1 | UniProt (P05749) Pfam (PF01776) | Saccharomyces cerevisiae (baker's yeast) | L1c,Large ribosomal subunit protein eL22-A,RP4,YL31 |
| 25 | Y (AL23) | 60S ribosomal protein L23-A | polymer | 137 | 14494.0 | 1 | UniProt (P0CX41) Pfam (PF00238) | Saccharomyces cerevisiae (baker's yeast) | L17a,Large ribosomal subunit protein uL14-A,YL32 |
| 26 | Z (AL24) | RPL24A isoform 1 | polymer | 155 | 17661.7 | 1 | UniProt (A0A6A5PY83) | Saccharomyces cerevisiae (baker's yeast) | |
| 27 | AA (AL25) | 60S ribosomal protein L25 | polymer | 142 | 15787.6 | 1 | UniProt (P04456) Pfam (PF03939) Pfam (PF00276) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein uL23,RP16L,YL25,YP42' |
| 28 | BA (AL26) | 60S ribosomal protein L26-A | polymer | 127 | 14265.8 | 1 | UniProt (P05743) Pfam (PF16906) Pfam (PF00467) | Saccharomyces cerevisiae (baker's yeast) | L33,Large ribosomal subunit protein uL24-A,YL33 |
| 29 | CA (AL27) | 60S ribosomal protein L27-A | polymer | 136 | 15568.4 | 1 | UniProt (P0C2H6) Pfam (PF01777) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL27-A |
| 30 | DA (AL28) | 60S ribosomal protein L28 | polymer | 149 | 16761.7 | 1 | UniProt (P02406) Pfam (PF00828) | Saccharomyces cerevisiae (baker's yeast) | L27a,L29,Large ribosomal subunit protein uL15,RP44,RP62,YL24 |
| 31 | EA (AL29) | RPL29 isoform 1 | polymer | 59 | 6691.9 | 1 | UniProt (A0A6A5PWR1) | Saccharomyces cerevisiae (baker's yeast) | |
| 32 | FA (AL30) | 60S ribosomal protein L30 | polymer | 105 | 11430.4 | 1 | UniProt (P14120) Pfam (PF01248) | Saccharomyces cerevisiae (baker's yeast) | L32,Large ribosomal subunit protein eL30,RP73,YL38 |
| 33 | GA (AL31) | 60S ribosomal protein L31-A | polymer | 113 | 12980.2 | 1 | UniProt (P0C2H8) Pfam (PF01198) | Saccharomyces cerevisiae (baker's yeast) | L34,Large ribosomal subunit protein eL31-A,YL28 |
| 34 | HA (AL32) | RPL32 isoform 1 | polymer | 130 | 14809.4 | 1 | UniProt (A0A6A5Q1M9) | Saccharomyces cerevisiae (baker's yeast) | |
| 35 | IA (AL33) | 60S ribosomal protein L33-A | polymer | 107 | 12177.1 | 1 | UniProt (P05744) Pfam (PF01247) | Saccharomyces cerevisiae (baker's yeast) | L37,Large ribosomal subunit protein eL33-A,RP47,YL37 |
| 36 | JA (AL34) | 60S ribosomal protein L34-A | polymer | 121 | 13673.2 | 1 | UniProt (P87262) Pfam (PF01199) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein eL34-A |
| 37 | KA (AL35) | 60S ribosomal protein L35-A | polymer | 120 | 13942.6 | 1 | UniProt (P0CX84) Pfam (PF00831) | Saccharomyces cerevisiae (baker's yeast) | Large ribosomal subunit protein uL29-A |
| 38 | LA (AL36) | 60S ribosomal protein L36-A | polymer | 100 | 11151.3 | 1 | UniProt (P05745) Pfam (PF01158) | Saccharomyces cerevisiae (baker's yeast) | L39,Large ribosomal subunit protein eL36-A,YL39 |
| 39 | MA (AL37) | 60S ribosomal protein L37-A | polymer | 88 | 9877.4 | 1 | UniProt (P49166) Pfam (PF01907) | Saccharomyces cerevisiae (baker's yeast) | L43,Large ribosomal subunit protein eL37-A,YL35,YP55 |
| 40 | NA (AL38) | RPL38 isoform 1 | polymer | 78 | 8845.6 | 1 | UniProt (A0A6A5PUL8) | Saccharomyces cerevisiae (baker's yeast) | |
| 41 | OA (AL39) | 60S ribosomal protein L39 | polymer | 51 | 6358.6 | 1 | UniProt (P04650) Pfam (PF00832) | Saccharomyces cerevisiae (baker's yeast) | L46,Large ribosomal subunit protein eL39,YL40 |
| 42 | PA (AL40) | Ubiquitin-60S ribosomal protein L40 | polymer | 128 | 14583.1 | 1 | UniProt (P0CH08) Pfam (PF00240) Pfam (PF01020) | Saccharomyces cerevisiae (baker's yeast) | |
| 43 | QA (AL41) | 60S ribosomal protein L41-A | polymer | 25 | 3354.2 | 1 | UniProt (P0CX86) Pfam (PF05162) | Saccharomyces cerevisiae (baker's yeast) | L47,Large ribosomal subunit protein eL41-A,YL41 |
| 44 | RA (AL42) | 60S ribosomal protein L42-A | polymer | 106 | 12246.7 | 1 | UniProt (P0CX27) Pfam (PF00935) | Saccharomyces cerevisiae (baker's yeast) | L41,Large ribosomal subunit protein eL42-A,YL27,YP44 |
| 45 | SA (AL43) | 60S ribosomal protein L43-A | polymer | 92 | 10113.0 | 1 | UniProt (P0CX25) Pfam (PF01780) | Saccharomyces cerevisiae (baker's yeast) | L37a,Large ribosomal subunit protein eL43-A,YL35 |
| 46 | TA (ALP0) | 60S acidic ribosomal protein P0 | polymer | 221 | 23773.6 | 1 | UniProt (P05317) Pfam (PF00466) Pfam (PF17777) | Saccharomyces cerevisiae (baker's yeast) | A0,L10e,Large ribosomal subunit protein uL10 |
| 47 | UA (APTN) | tRNAfMet | polymer | 77 | 24802.8 | 1 | GenBank (1848934315) | Escherichia coli | |
| 48 | VA (PR) | PR20 | polymer | 40 | 5104.2 | 1 | UniProt (A7H9Z6) | Homo sapiens | |
| 49 | WA, XA, YA, ZA (AL37, AL40, AL42, AL43) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 48 |
| Total formula weight | 1997623.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 1997884.6 |
