7TNO
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera | polymer | 1033 | 115444.9 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF00822) UniProt (by SIFTS) (Q71RJ2) In PDB | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
2 | A, B, C | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) | |||
3 | A, B, C, D | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) |
Sequence modifications
A, B, C, D: 10 - 998 (UniProt: P19491)
A, B, C, D: 1001 - 1214 (PDB: 7TNO)
PDB | External Database | Details |
---|---|---|
Glu 241 | Asn 256 | conflict |
Leu 382 | Val 397 | conflict |
- | Leu 399 | deletion |
- | Thr 400 | deletion |
- | Glu 401 | deletion |
- | Leu 402 | deletion |
- | Pro 403 | deletion |
- | Ser 404 | deletion |
Glu 384 | Gly 405 | conflict |
Asp 385 | Asn 406 | conflict |
Gln 392 | Asn 413 | conflict |
Gly 999 | - | linker |
Thr 1000 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 461779.7 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2000.9 | |
All* | Total formula weight | 463780.6 |