7TNO
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera | polymer | 1033 | 115444.9 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF00822) UniProt (by SIFTS) (Q71RJ2) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, G, I (A, B, C) | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) | |||
| 3 | F, H, J, K (A, B, C, D) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) |
Sequence modifications
A, B, C, D: 10 - 998 (UniProt: P19491)
A, B, C, D: 1001 - 1214 (PDB: 7TNO)
| PDB | External Database | Details |
|---|---|---|
| Glu 241 | Asn 256 | conflict |
| Leu 382 | Val 397 | conflict |
| - | Leu 399 | deletion |
| - | Thr 400 | deletion |
| - | Glu 401 | deletion |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| Glu 384 | Gly 405 | conflict |
| Asp 385 | Asn 406 | conflict |
| Gln 392 | Asn 413 | conflict |
| Gly 999 | - | linker |
| Thr 1000 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 461779.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2000.9 | |
| All* | Total formula weight | 463780.6 |
