7TNI

Structure of EC12 Y1392W variant of BT-R1 from Manduca sexta, a Cry1A toxin binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Cadherin	polymer	155	16877.7	4	UniProt (Q8MZK3) UniProt (by SIFTS) (Q9GPJ9) In PDB	Manduca sexta (Tobacco hawkmoth Tobacco hornworm)
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3		water	water		18.0	227	Chemie (HOH)

Sequence modifications

A, B, C, D: 1349 - 1460 (UniProt: Q8MZK3)

PDB	External Database	Details
Met 1306	-	initiating methionine
Asn 1307	-	expression tag
Thr 1308	-	expression tag
Ile 1309	-	expression tag
His 1310	-	expression tag
His 1311	-	expression tag
His 1312	-	expression tag
His 1313	-	expression tag
His 1314	-	expression tag
His 1315	-	expression tag
Asn 1316	-	expression tag
Thr 1317	-	expression tag
Ser 1318	-	expression tag
Gly 1319	-	expression tag
Ser 1320	-	expression tag
Gly 1321	-	expression tag
Gly 1322	-	expression tag
Gly 1323	-	expression tag
Gly 1324	-	expression tag
Gly 1325	-	expression tag
Arg 1326	-	expression tag
Leu 1327	-	expression tag
Val 1328	-	expression tag
Pro 1329	-	expression tag
Arg 1330	-	expression tag
Gly 1331	-	expression tag
Ser 1332	-	expression tag
Met 1333	-	expression tag
Ser 1334	-	expression tag
Glu 1335	-	expression tag
Asn 1336	-	expression tag
Leu 1337	-	expression tag
Tyr 1338	-	expression tag
Phe 1339	-	expression tag
Gln 1340	-	expression tag
Gly 1341	-	expression tag
Ser 1342	-	expression tag
Met 1343	-	expression tag
Asp 1344	-	expression tag
Ile 1345	-	expression tag
Glu 1346	-	expression tag
Phe 1347	-	expression tag
Val 1348	-	expression tag
Val 1355	Met 1355	conflict
Ser 1384	Ala 1384	conflict
Trp 1392	Tyr 1392	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67510.9
Non-Polymers*	Number of molecules	4
	Total formula weight	97.2
All*	Total formula weight	67608.1

*Water molecules are not included.