7TKX
Crystal structure of R14A human Galectin-7 mutant in presence of 4-O-beta-D-Galactopyranosyl-D-glucose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-7 | polymer | 135 | 14879.7 | 2 | UniProt (P47929) Pfam (PF00337) | Homo sapiens (human) | Gal-7,HKL-14,PI7,p53-induced gene 1 protein |
| 2 | C, G (A, B) | (2~{R},3~{R},4~{R},5~{R})-4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3,5, 6-tetrakis(oxidanyl)hexanal | non-polymer | 342.3 | 2 | Chemie (LBL) | |||
| 3 | D, E, H, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 135 (UniProt: P47929)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Arg 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29759.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1025.0 | |
| All* | Total formula weight | 30784.4 |
