7TKX
Crystal structure of R14A human Galectin-7 mutant in presence of 4-O-beta-D-Galactopyranosyl-D-glucose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-7 | polymer | 135 | 14879.7 | 2 | UniProt (P47929) Pfam (PF00337) | Homo sapiens (human) | Gal-7,HKL-14,PI7,p53-induced gene 1 protein |
| 2 | C, G (A, B) | (2~{R},3~{R},4~{R},5~{R})-4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3,5, 6-tetrakis(oxidanyl)hexanal | non-polymer | 342.3 | 2 | Chemie (LBL) PubChem (128037) PubChem (181526) PubChem (493593) PubChem (3037558) PubChem (21120113) PubChem (21123109) PubChem (23657858) PubChem (24751717) PubChem (176975890) PubChem (177706954) PubChem (20056755) PubChem (21123108) PubChem (50987233) PubChem (121941) PubChem (303614) PubChem (92024244) PubChem (92024243) PubChem (53393680) PubChem (121434384) PubChem (6857391) PubChem (57358734) PubChem (57519464) PubChem (133109111) PubChem (174823103) PubChem (71771811) PubChem (87962983) PubChem (88101068) PubChem (91696346) PubChem (92222678) PubChem (92222679) PubChem (92222680) PubChem (92223571) PubChem (101103826) PubChem (101289693) PubChem (121434396) PubChem (124918766) PubChem (124918767) PubChem (124918768) PubChem (124918769) PubChem (125508879) PubChem (129629370) PubChem (134834577) PubChem (135056408) PubChem (135328609) PubChem (154075397) PubChem (155165458) PubChem (157043240) PubChem (162962859) PubChem (162962860) PubChem (162962861) PubChem (166691201) PubChem (168951318) | |||
| 3 | D, E, H, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 135 (UniProt: P47929)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Arg 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29759.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1025.0 | |
| All* | Total formula weight | 30784.4 |
