7TJ4

Structure of the S. aureus amidase LytH and activator ActH extracellular domains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	ActH	polymer	122	14010.7	2	UniProt (A0A2X3YEX3) UniProt (by SIFTS) (Q2FY25)	Staphylococcus aureus	Rhomboid protease GluP
2	B, D (B, D)	LytH	polymer	176	19681.0	2	UniProt (O32421) Pfam (PF01520) UniProt (by SIFTS) (Q2FXU3)	Staphylococcus aureus
3	E, F (B, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	G, H, I, J (A, B, C, D)	water	water		18.0	319	Chemie (HOH)

Sequence modifications

A, C: 365 - 479 (UniProt: A0A2X3YEX3)

PDB	External Database	Details
Glu -7	-	expression tag
Val -6	-	expression tag
Leu -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag

B, D: 117 - 291 (UniProt: O32421)

PDB	External Database	Details
Met -1	-	initiating methionine
Ala 245	Arg 245	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67383.4
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	67514.3

*Water molecules are not included.