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7TEV

Human Ornithine Aminotransferase cocrystallized with its inhibitor, (3S,4R)-3-amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, COrnithine aminotransferase, mitochondrialpolymer40444860.33UniProt (P04181)
Pfam (PF00202)
In PDB
Homo sapiens (human)Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase
2A, B, C(1S,3R,4S)-3-formyl-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopentane-1-carboxylic acidnon-polymer388.33Chemie (I1T)
3waterwater18.0592Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight134581.0
Non-Polymers*Number of molecules3
Total formula weight1164.9
All*Total formula weight135745.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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