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7TED

Human Ornithine Aminotransferase cocrystallized with its inhibitor, (S,E)-3-amino-4-(fluoromethylene)cyclopent-1-ene-1-carboxylate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Ornithine aminotransferase, mitochondrialpolymer40444860.39UniProt (P04181)
Pfam (PF00202)
Homo sapiens (human)Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase
2J, K, L, M, N...
(A, B, C, D, E...)
(1S,3R,4S)-3-formyl-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopentane-1-carboxylic acidnon-polymer388.38Chemie (I1T)
3R
(I)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
4AA, S, T, U, V...
(I, A, B, C, D...)
waterwater18.0335Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight403742.9
Non-Polymers*Number of molecules9
Total formula weight3353.6
All*Total formula weight407096.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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