7TDY

The ubiquitin-associated domain of human thirty-eight negative kinase 1, flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at low protein concentration

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1	polymer	155	17775.1	1	UniProt (P41212) UniProt (Q13470) Pfam (PF02198) In PDB	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,CD38 negative kinase 1
2	A	FORMIC ACID	non-polymer		46.0	6	Chemie (FMT)
3		water	water		18.0	70	Chemie (HOH)

Sequence modifications

A: 2 - 75 (UniProt: P41212)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 35	Arg 80	engineered mutation
Glu 67	Val 112	engineered mutation
Leu 76	-	linker
Gly 77	-	linker
Gly 78	-	linker

A: 79 - 155 (UniProt: Q13470)

PDB	External Database	Details
Ala 99	Cys 610	engineered mutation
Ala 133	Cys 644	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17775.1
Non-Polymers*	Number of molecules	6
	Total formula weight	276.1
All*	Total formula weight	18051.2

*Water molecules are not included.