7TDY
The ubiquitin-associated domain of human thirty-eight negative kinase 1, flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at low protein concentration
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1 | polymer | 155 | 17775.1 | 1 | UniProt (P41212) UniProt (Q13470) Pfam (PF02198) In PDB | Homo sapiens (human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,CD38 negative kinase 1 |
2 | A | FORMIC ACID | non-polymer | 46.0 | 6 | Chemie (FMT) | |||
3 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 2 - 75 (UniProt: P41212)
A: 79 - 155 (UniProt: Q13470)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Ser 35 | Arg 80 | engineered mutation |
Glu 67 | Val 112 | engineered mutation |
Leu 76 | - | linker |
Gly 77 | - | linker |
Gly 78 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 99 | Cys 610 | engineered mutation |
Ala 133 | Cys 644 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 17775.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 276.1 | |
All* | Total formula weight | 18051.2 |