7TDL
M379A mutant tyrosine phenol-lyase complexed with 3-bromo-DL-phenylalanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Tyrosine phenol-lyase | polymer | 456 | 51448.6 | 4 | UniProt (P31013) Pfam (PF01212) In PDB | Citrobacter freundii | Beta-tyrosinase |
| 2 | A, C | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 3 | A, B | (4Z)-4-({[(1E)-2-(3-bromophenyl)-1-carboxyethylidene]azaniumyl}methylidene)-2-methyl-5-[(phosphonooxy)methyl]-1,4-dihydropyridin-3-olate | non-polymer | 473.2 | 2 | Chemie (OY3) | |||
| 4 | A, C, D | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | A, C, D | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | B, C, D | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 3 | Chemie (PLP) | |||
| 7 | water | water | 18.0 | 1528 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 456 (UniProt: P31013)
| PDB | External Database | Details |
|---|---|---|
| Ala 205 | Glu 205 | conflict |
| Ala 379 | Met 379 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 205794.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2263.1 | |
| All* | Total formula weight | 208057.7 |
