7TD9

G-059 bound to the SMARCA4 (BRG1) Bromodomain

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB, CCC	Isoform 4 of Transcription activator BRG1	polymer	130	15104.2	3	UniProt (P51532-4) In PDB	Homo sapiens (human)	ATP-dependent helicase SMARCA4,BRG1-associated factor 190A,BAF190A,Mitotic growth and transcription activator,Protein BRG-1,Protein brahma homolog 1,SNF2-beta,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
2	AAA, BBB, CCC	4-phenyl-5H-pyridazino[4,3-b]indol-3-amine	non-polymer		260.3	3	Chemie (GJN)
3		water	water		18.0	229	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC: 1448 - 1575 (UniProt: P51532-4)

PDB	External Database	Details
Gly 1446	-	expression tag
Ser 1447	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	45312.7
Non-Polymers*	Number of molecules	3
	Total formula weight	780.9
All*	Total formula weight	46093.6

*Water molecules are not included.