7TCZ

Human cytomegalovirus protease mutant (C84A, C87A, C138A, C202A) in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Assemblin	polymer	263	28961.4	1	UniProt (A0A126N917) Pfam (PF00716) UniProt (by SIFTS) (P16753)	Human betaherpesvirus 5	Protease
2	B (A)	[1-(2-oxopropyl)-4-phenyl-1H-1,2,3-triazol-5-yl]methyl benzylcarbamate	non-polymer		364.4	1	Chemie (GIT)
3	C (A)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 1 - 256 (UniProt: A0A126N917)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ala 84	Cys 84	engineered mutation
Ala 87	Cys 87	engineered mutation
Ala 138	Cys 138	engineered mutation
Val 143	Ala 143	engineered mutation
Ala 202	Cys 202	engineered mutation
Val 209	Ala 209	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28961.4
Non-Polymers*	Number of molecules	1
	Total formula weight	364.4
All*	Total formula weight	29325.8

*Water molecules are not included.