7TBZ
The structure of ABCA1 Y482C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette, sub-family A (ABC1), member 1 | polymer | 2270 | 255595.0 | 1 | UniProt (B2RUU2) Pfam (PF12698) Pfam (PF00005) UniProt (by SIFTS) (O95477) | Homo sapiens (human) | |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (C) | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G89225LT) | |||
| 4 | D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | F (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
A: 1 - 2261 (UniProt: B2RUU2)
| PDB | External Database | Details |
|---|---|---|
| Cys 482 | Tyr 482 | engineered mutation |
| Gly 2262 | - | expression tag |
| Asp 2263 | - | expression tag |
| Tyr 2264 | - | expression tag |
| Lys 2265 | - | expression tag |
| Asp 2266 | - | expression tag |
| Asp 2267 | - | expression tag |
| Asp 2268 | - | expression tag |
| Asp 2269 | - | expression tag |
| Lys 2270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 255595.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 829.1 | |
| All* | Total formula weight | 257759.2 |
