7TB4
Cryo-EM structure of the spike of SARS-CoV-2 Omicron variant of concern
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Surface glycoprotein | polymer | 1192 | 132465.1 | 3 | UniProt (A0A8A4XEV3) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (P0DTC2) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
2 | D, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 15 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 29 | Chemie (NAG) |
Sequence modifications
A, B, C: 14 - 1208 (UniProt: A0A8A4XEV3)
PDB | External Database | Details |
---|---|---|
Val 67 | Ala 67 | conflict |
- | His 69 | deletion |
- | Val 70 | deletion |
Ile 95 | Thr 95 | conflict |
- | Asn 208 | deletion |
Ile 212 | Leu 209 | conflict |
Glu 214 | - | insertion |
Pro 214 | - | insertion |
Glu 214 | - | insertion |
Asp 339 | Gly 336 | conflict |
Leu 371 | Ser 368 | conflict |
Pro 373 | Ser 370 | conflict |
Phe 375 | Ser 372 | conflict |
Asn 417 | Lys 414 | conflict |
Lys 440 | Asn 437 | conflict |
Ser 446 | Gly 443 | conflict |
Asn 477 | Ser 474 | conflict |
Lys 478 | Thr 475 | conflict |
Ala 484 | Arg 481 | conflict |
Arg 493 | Gln 490 | conflict |
Ser 496 | Gly 493 | conflict |
Arg 498 | Gln 495 | conflict |
Tyr 501 | Asn 498 | conflict |
His 505 | Tyr 502 | conflict |
Lys 547 | Thr 544 | conflict |
Tyr 655 | His 652 | conflict |
Lys 679 | Asn 676 | conflict |
His 681 | Pro 678 | conflict |
Gly 682 | Arg 679 | conflict |
Ser 683 | Arg 680 | conflict |
Ser 685 | Arg 682 | conflict |
Lys 764 | Asn 761 | conflict |
Tyr 796 | Asp 793 | conflict |
Lys 856 | Asn 853 | conflict |
His 954 | Gln 951 | conflict |
Lys 969 | Asn 966 | conflict |
Phe 981 | Leu 978 | conflict |
Pro 986 | Lys 983 | conflict |
Pro 987 | Val 984 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 397395.3 | |
Branched | Number of molecules | 15 |
Total formula weight | 6366.0 | |
Non-Polymers* | Number of molecules | 29 |
Total formula weight | 6415.0 | |
All* | Total formula weight | 410176.3 |