7TAO
Cryo-EM structure of bafilomycin A1 bound to yeast VO V-ATPase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | V-type proton ATPase subunit c' | polymer | 164 | 17046.4 | 1 | UniProt (P32842) Pfam (PF00137) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase subunit c',Proteolipid protein VMA11,Trifluoperazine resistance protein 3,V-ATPase 16 kDa proteolipid subunit 2,Vacuolar proton pump c' subunit |
| 2 | B (C) | V-type proton ATPase subunit c'' | polymer | 213 | 22610.6 | 1 | UniProt (P23968) Pfam (PF00137) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase subunit c'',V-ATPase 22 kDa proteolipid subunit,Vacuolar proton pump c'' subunit |
| 3 | C (N) | V0 assembly protein 1 | polymer | 265 | 29694.9 | 1 | UniProt (P53262) Pfam (PF20520) | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | D (M) | V-type proton ATPase subunit e | polymer | 73 | 8387.1 | 1 | UniProt (Q3E7B6) Pfam (PF05493) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase subunit e,Low dye-binding protein 10,Vacuolar proton pump subunit e |
| 5 | E, G, H, I, J... (E, F, G, H, I...) | V-type proton ATPase subunit c | polymer | 160 | 16357.5 | 8 | UniProt (P25515) Pfam (PF00137) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase subunit c,Guanine nucleotide exchange factor 2,V-ATPase 16 kDa proteolipid subunit 1,Vacuolar proton pump c subunit |
| 6 | F (O) | Yeast V-ATPase subunit f | polymer | 85 | 9369.9 | 1 | UniProt (P0C5R9) | Saccharomyces cerevisiae (baker's yeast) | |
| 7 | N (B) | V-type proton ATPase subunit d | polymer | 345 | 39822.5 | 1 | UniProt (P32366) Pfam (PF01992) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase subunit d,V-ATPase 39 kDa subunit,V-ATPase subunit M39,Vacuolar proton pump subunit d |
| 8 | O (A) | V-type proton ATPase subunit a, vacuolar isoform | polymer | 840 | 95625.5 | 1 | UniProt (P32563) Pfam (PF01496) | Saccharomyces cerevisiae (baker's yeast) | V-ATPase a 1 subunit,V-ATPase 95 kDa subunit,Vacuolar pH protein 1,Vacuolar proton pump a subunit,Vacuolar proton translocating ATPase subunit a 1 |
| 9 | P, Q, R, S, T... (D, E, F, G, H...) | (5R)-2,4-dideoxy-1-C-{(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4E,6E,9R,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl}-4-methyl-5-propan-2-yl-alpha-D-threo-pentopyranose | non-polymer | 622.8 | 9 | Chemie (WEV) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 353416.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 5605.5 | |
| All* | Total formula weight | 359022.3 |
