7T9H
HIV Integrase in complex with Compound-15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Integrase | polymer | 166 | 18121.6 | 2 | UniProt (Q76353) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, F (A, B) | (2S)-tert-butoxy[2-methyl-4-(4-methylphenyl)quinolin-3-yl]acetic acid | non-polymer | 363.4 | 2 | Chemie (GE7) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 47 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Ser 48 | Glu 48 | conflict |
| His 49 | Ala 49 | conflict |
| Ser 56 | Cys 56 | conflict |
| Glu 131 | Trp 131 | conflict |
| Lys 185 | Phe 185 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36243.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 775.5 | |
| All* | Total formula weight | 37018.7 |
