7T7H
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA repair NTP-phosphohydrolase | polymer | 221 | 26102.1 | 2 | UniProt (L7QJE0) Pfam (PF00293) UniProt (by SIFTS) (P04311) | Vaccinia virus Western Reserve | MutT motif/mRNA decapping enzyme,NTP-phosphohydrolase,Putative D9R |
| 2 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | E, F (A, B) | 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine | non-polymer | 560.6 | 2 | Chemie (G7R) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 213 (UniProt: L7QJE0)
| PDB | External Database | Details |
|---|---|---|
| Leu 214 | - | expression tag |
| Glu 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52204.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1167.3 | |
| All* | Total formula weight | 53371.4 |
