7T79
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND AKA DIETHYL {[3-(3-{[5-(AZETIDINE-1-CARBON YL)PYRAZIN-2-YL]OXY}-5-(PROPAN-2-YLOXY)BENZAMIDO)-1H- PYRAZOL-1-YL]METHYL}PHOSPHONATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 2 of Hexokinase-4 | polymer | 466 | 52199.3 | 2 | UniProt (P35557) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (human) | HK4,Glucokinase,Hexokinase type IV,HK IV,Hexokinase-D |
| 2 | C, E (A, B) | diethyl {[3-(3-{[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy}-5-[(propan-2-yl)oxy]benzamido)-1H-pyrazol-1-yl]methyl}phosphonate | non-polymer | 572.5 | 2 | Chemie (G1S) | |||
| 3 | D, F (A, B) | alpha-D-glucopyranose | non-polymer | 180.2 | 2 | Chemie (GLC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104398.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1505.4 | |
| All* | Total formula weight | 105904.0 |
