7T6T
Structure of the human FPR1-Gi complex with fMLFII
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40313.9 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (Human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 353 | 39021.6 | 1 | UniProt (P54311) Pfam (PF00400) | Rattus | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P63212) Pfam (PF00631) | Bos taurus (Cattle) | G gamma-I |
| 4 | D (L) | Synthetic peptide | polymer | 5 | 663.9 | 1 | Homo | ||
| 5 | E (R) | fMet-Leu-Phe receptor | polymer | 354 | 39041.7 | 1 | UniProt (P21462) Pfam (PF00001) | Homo sapiens (Human) | fMLP receptor,N-formyl peptide receptor,FPR,N-formylpeptide chemoattractant receptor |
| 6 | F, G (R) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) |
Sequence modifications
A: 2 - 354 (UniProt: P63096)
B: 2 - 340 (UniProt: P54311)
R: 1 - 333 (UniProt: P21462)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | conflict |
| Ser 326 | Ala 326 | conflict |
| PDB | External Database | Details |
|---|---|---|
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| Met -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
| Glu 6 | Gln 6 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asp -20 | - | expression tag |
| Tyr -19 | - | expression tag |
| Lys -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Val -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Asn -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 126473.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 512.8 | |
| All* | Total formula weight | 126986.5 |
