7T6C

E. coli dihydroorotate dehydrogenase bound to the ubiquinone surrogate DCIP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydroorotate dehydrogenase (quinone)	polymer	368	40285.3	2	UniProt (P0A7E1) Pfam (PF01180)	Escherichia coli K-12	DHOdehase,DHOD,DHODase,Dihydroorotate oxidase
2	C (A)	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
3	D, H (A, B)	OROTIC ACID	non-polymer		156.1	2	Chemie (ORO)
4	E, I (A, B)	2,6-bis(chloranyl)-4-[(4-hydroxyphenyl)amino]phenol	non-polymer		270.1	2	Chemie (RLM)
5	F, J (A, B)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
6	G (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	K, L (A, B)	water	water		18.0	110	Chemie (HOH)

Sequence modifications

A, B: 1 - 336 (UniProt: P0A7E1)

PDB	External Database	Details
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Leu -22	-	expression tag
Val -21	-	expression tag
Pro -20	-	expression tag
Arg -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Ala -14	-	expression tag
Ser -13	-	expression tag
Met -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gln -8	-	expression tag
Gln -7	-	expression tag
Met -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80570.5
Non-Polymers*	Number of molecules	8
	Total formula weight	2211.6
All*	Total formula weight	82782.1

*Water molecules are not included.