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7T5P

Cryo-EM structure of human SIMC1-SLF2 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SUMO-interacting motif-containing protein 1polymer58967021.51UniProt (Q8NDZ2)Homo sapiens (human)Platform element for inhibition of autolytic degradation
2B
(B)
SMC5-SMC6 complex localization factor protein 2polymer53961867.81UniProt (Q8IX21)
Pfam (PF14816)
Homo sapiens (human)Smc5/6 localization factor 1
Sequence modifications
A: 284 - 872 (UniProt: Q8NDZ2)
PDBExternal DatabaseDetails
Arg 379Ser 379conflict
Arg 463Lys 463variant
Arg 772His 772variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight128889.3
All*Total formula weight128889.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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