7T3V

Metal dependent activation of Plasmodium falciparum M17 aminopeptidase, spacegroup P22121 after crystals soaked with Zn2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	M17 leucyl aminopeptidase	polymer	527	58577.8	6	UniProt (Q8IL11) Pfam (PF00883) In PDB	Plasmodium falciparum (malaria parasite P. falciparum)
2	A, B, C, D, E...	CARBONATE ION	non-polymer		60.0	6	Chemie (CO3)
3	F, A, B, C, D...	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
4	C, D	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
5	C, E	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6		water	water		18.0	279	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 85 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	conflict
Gln 515	Asn 515	conflict
Gln 546	Asn 546	conflict
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	351466.7
Non-Polymers*	Number of molecules	22
	Total formula weight	1573.4
All*	Total formula weight	353040.1

*Water molecules are not included.