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7T3U

IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the inactive state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Inositol 1,4,5-trisphosphate receptor type 3polymer2633299325.94UniProt (Q14573)
Pfam (PF08709)
Pfam (PF02815)
Pfam (PF01365)
Pfam (PF08454)
Pfam (PF00520)
Homo sapiens (human)IP3 receptor isoform 3,IP3R 3,InsP3R3,Type 3 inositol 1,4,5-trisphosphate receptor,Type 3 InsP3 receptor
2E, I, L, O
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
3F, P
(A, D)
D-MYO-INOSITOL-1,4,5-TRIPHOSPHATEnon-polymer420.12Chemie (I3P)
4G, J, M, Q
(A, B, C, D)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.24Chemie (ATP)
5H, K, N, R
(A, B, C, D)
CALCIUM IONnon-polymer40.14Chemie (CA)
Sequence modifications
A, B, C, D: 1 - 2611 (UniProt: Q14573)
A, B, C, D: 2612 - 2633 (PDB: 7T3U)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight1197303.5
Non-Polymers*Number of molecules14
Total formula weight3290.9
All*Total formula weight1200594.4
*Water molecules are not included.

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PDB entries from 2025-08-06

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