7T1H
Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU281445
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pantothenate kinase CAB1 | polymer | 375 | 41974.2 | 2 | UniProt (Q04430) Pfam (PF03630) | Saccharomyces cerevisiae S288C | Coenzyme A biosynthesis protein 1,Pantothenic acid kinase CAB1 |
| 2 | C (A) | (8R)-2-{[(4-tert-butylphenyl)methyl]amino}-5-[(morpholin-4-yl)methyl][1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | non-polymer | 396.5 | 1 | Chemie (E5B) | |||
| 3 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 367 (UniProt: Q04430)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83948.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 488.6 | |
| All* | Total formula weight | 84437.0 |
