7T1G

Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU385595

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Pantothenate kinase CAB1	polymer	375	41974.2	2	UniProt (Q04430) Pfam (PF03630) In PDB	Saccharomyces cerevisiae S288C	Coenzyme A biosynthesis protein 1,Pantothenic acid kinase CAB1
2	B	(8S)-N~2~-[(4-tert-butylphenyl)methyl]-N~7~,N~7~-dimethyl-5-[(morpholin-4-yl)methyl][1,2,4]triazolo[1,5-a]pyrimidine-2,7-diamine	non-polymer		423.6	1	Chemie (E66)
3		water	water		18.0	204	Chemie (HOH)

Sequence modifications

A, B: 1 - 367 (UniProt: Q04430)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83948.4
Non-Polymers*	Number of molecules	1
	Total formula weight	423.6
All*	Total formula weight	84371.9

*Water molecules are not included.