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7T0L

HLA-B*27:05 in complex with the pan-HLA-Ia monoclonal antibody W6/32

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, DMHC class I antigenpolymer27631911.12UniProt (A3F718)
Pfam (PF00129)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
2B, EBeta-2-microglobulinpolymer9911748.22UniProt (P61769)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
3C, FPHE-ARG-TYR-ASN-GLY-LEU-ILE-HIS-ARG peptidepolymer91178.42synthetic construct
4G, HIgG2a heavy chainpolymer21823245.12Mus musculus (Mouse)
5K, LLight chain kappapolymer21123386.82Mus musculus (Mouse)
Sequence modifications
A, D: 1 - 276 (UniProt: A3F718)
PDBExternal DatabaseDetails
Ser 67Cys 77engineered mutation
Asn 116Asp 126conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight182939.1
All*Total formula weight182939.1
*Water molecules are not included.

224931

PDB entries from 2024-09-11

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