7T0L
HLA-B*27:05 in complex with the pan-HLA-Ia monoclonal antibody W6/32
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | MHC class I antigen | polymer | 276 | 31911.1 | 2 | UniProt (A3F718) | Homo sapiens (Human) | |
| 2 | B, E (B, E) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, F (C, F) | PHE-ARG-TYR-ASN-GLY-LEU-ILE-HIS-ARG peptide | polymer | 9 | 1178.4 | 2 | synthetic construct | ||
| 4 | G, H (G, H) | IgG2a heavy chain | polymer | 218 | 23245.1 | 2 | Mus musculus (Mouse) | ||
| 5 | I, J (K, L) | Light chain kappa | polymer | 211 | 23386.8 | 2 | Mus musculus (Mouse) |
Sequence modifications
A, D: 1 - 276 (UniProt: A3F718)
| PDB | External Database | Details |
|---|---|---|
| Ser 67 | Cys 77 | engineered mutation |
| Asn 116 | Asp 126 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 182939.1 | |
| All* | Total formula weight | 182939.1 |
