7SXG
BIO-8546 bound GSK3alpha-axin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycogen synthase kinase-3 alpha | polymer | 343 | 39046.0 | 1 | UniProt (P49840) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 alpha,Serine/threonine-protein kinase GSK3A |
| 2 | B (B) | Axin peptide | polymer | 18 | 2137.5 | 1 | UniProt (by SIFTS) (O15169) | Homo sapiens | |
| 3 | C (A) | (4S,5R,8R)-4-ethyl-8-fluoro-4-[3-(3-fluoro-5-methoxypyridin-4-yl)phenyl]-7,7-dimethyl-4,5,6,7,8,9-hexahydro-2H-pyrazolo[3,4-b]quinolin-5-ol | non-polymer | 466.5 | 1 | Chemie (D1E) | |||
| 4 | D (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41183.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 41650.0 |
