7SWY

2.6 A structure of a 40-601[TA-rich+1]-40 nucleosome

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3	polymer	135	15271.9	2	UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) In PDB	Xenopus laevis (African clawed frog)
2	B, F	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
3	C, G	Histone H2A	polymer	129	13978.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211) In PDB	Xenopus laevis (African clawed frog)
4	D, H	Histone H2B	polymer	122	13540.8	2	UniProt (A0A1L8FQ56) Pfam (PF00125) UniProt (by SIFTS) (P02281) In PDB	Xenopus laevis (African clawed frog)
5	I	DNA Tracking Strand	polymer	226	69501.2	1		synthetic construct
6	J	DNA Guide Strand	polymer	226	70066.6	1		synthetic construct

Sequence modifications

A, E: 1 - 135 (UniProt: A0A310TTQ1)

PDB	External Database	Details
Ala 110	Cys 111	engineered mutation

C, G: 1 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	engineered mutation
Ser 123	Ala 124	engineered mutation

D, H: 1 - 122 (UniProt: A0A1L8FQ56)

PDB	External Database	Details
Pro 7	Ala 11	conflict
Cys 53	Ser 57	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	247676.1
All*	Total formula weight	247676.1

*Water molecules are not included.