7SVX
Structure of EmrE-D3 mutant in complex with monobody L10 and harmane
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Multidrug transporter EmrE | polymer | 110 | 11907.3 | 2 | UniProt (P23895) Pfam (PF00893) | Escherichia coli (strain K12) | Efflux-multidrug resistance protein EmrE,Ethidium resistance protein,Methyl viologen resistance protein C |
| 2 | B, D (C, D) | L10 monobody | polymer | 91 | 9931.9 | 2 | Homo sapiens (Human) | ||
| 3 | E (B) | 1-methyl-9H-pyrido[3,4-b]indole | non-polymer | 182.2 | 1 | Chemie (CN9) |
Sequence modifications
A, B: 1 - 110 (UniProt: P23895)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Glu 25 | engineered mutation |
| Ile 31 | Trp 31 | engineered mutation |
| Met 34 | Val 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43678.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 182.2 | |
| All* | Total formula weight | 43860.6 |
