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7SVC

NMR structure of cTnC-TnI chimera bound to calcium and A2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac musclepolymer12914222.11UniProt (P63316)
UniProt (P19429)
Pfam (PF13833)
Homo sapiens (human)TN-C,Cardiac troponin I
2B
(A)
4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3R,4S)-7-fluoro-4-hydroxy-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamidenon-polymer462.51Chemie (C9W)
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
Sequence modifications
A: 2 - 91 (UniProt: P63316)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 92-linker
Gly 93-linker
Ala 94-linker
Gly 95-linker
A: 96 - 129 (UniProt: P19429)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14222.1
Non-Polymers*Number of molecules2
Total formula weight502.6
All*Total formula weight14724.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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